In addition to the positive effect of clomiphene, as with many other drugs, there may be some side effects:
Significant weight gain
Blurred and blurred vision
Changes in normal sleep quality and rhythm
Heavy bleeding during menstruation
Sensations of heat tide
Another side effect of clomiphene is dry cervical mucosa, which can affect the quality of intercourse; however, this defect can be compensated by the use of a vaginal lubricant.
As a side effect, OHS (ovarian hyperstimulation syndrome) may occur. This condition is characterized by a reversible increase (edema) of the ovaries due to the body’s active response to hormones and is quite common (> 10% of women). EHH should be suspected if excessive flatulence or abdominal distention occurs. This can be a serious problem, but usually ovarian hyperstimulation syndrome, caused by the use of clostilbegit, is a mild condition that resolves on its own. The severity of OHSS can increase if you take hCG (another medication to improve fertility).
Clomiphene can lead to multiple ovulation, therefore, increases the likelihood of twins (10% of births instead of ~ 1% without it) and triplets.
Some studies have shown that clomiphene, when used for more than a year, may increase the risk of ovarian cancer. Subsequent studies did not confirm these findings, so it is impossible to talk about this with confidence.
The incidence of fetus in the application of clomiphene according to statistics does not exceed the level that is observed during conception without it. There is no evidence of a higher number of congenital abnormalities or spontaneous abortions after using this drug. Although there are also studies that show that the number of congenital heart abnormalities is significantly higher with its use than with its analogue for ovarian stimulation - letrozole.